| ABC Adoption |
| Alzheimer's Association, Central and Western Virginia Chapter |
| American Cancer Society - South Atlantic Division |
| American Diabetes Association, Virginia Affiliate |
| American Heart Association, Virginia Affiliate |
| American Lung Association of Virginia, Roanoke Region; |
| American Red Cross, Bedford Chapter |
| Apple Ridge Farm, Inc. |
| Arthritis Foundation, Virginia Chapter, Southwest Virginia Branch |
| Back Creek Fire & Rescue Department |
| Bent Mountain First Aid & Rescue Crew |
| Blue Ridge Autism Center |
| Blue Ridge Housing Development Corporation |
| Blue Ridge Independent Living Center |
| Blue Ridge Volunteer Fire and Rescue Department |
| Boy's Home, Inc. |
| Bradley Free Clinic of Roanoke Valley |
| Brain Injury Services of Southwest Virginia |
| Camp Virginia Jaycees |
| CASA Foundation - Roanoke Valley |
| CASA of Central Virginia (Lynchburg) |
Cave Spring First Aid and Rescue Squad
Cave Spring Volunteer Fire Department |
| Chamblissburg First Aid & Rescue Squad, Inc. |
| Clean Valley Council |
| Commonwealth Autism Service |
| Commonwealth Search & Rescue |
| Conflict Resolution Center |
| Craig County New Castle Volunteer Fire Dept. |
| Crisis Line of Central Virginia |
| Dare to Care Charities, Inc. |
| DePaul Family Services |
| Down Syndrome Association of Roanoke |
| Downtown Learning Center |
| Downtown Music Lab |
| Easter Seals Virginia |
| Fincastle Rescue Squad |
| Floyd County Life Saving & First Aid Squad |
| Fort Lewis Volunteer Fire Department |
| Foundation for Rehabilitation Equipment & Endowment (Free) |
| Franklin County Rescue Squad |
| Franklin County Youth Center |
| Free Clinic of Franklin County |
| Glade Hill Rescue Squad |
| Good Samaritan Hospice |
| Habitat for Humanity in the Roanoke Valley |
| Hardy Life Saving & Rescue |
| Health Focus of Southwest Virginia |
| Hollins Fire and Rescue Squad |
| Juvenile Diabetes International |
| Kid's Haven: A Center for Grieving Children |
| Literacy Volunteers of Roanoke Valley |
| Lupus Foundation of America-Roanoke Valley Branch |
| Lutheran Family Services of Virginia |
| Make A Wish Foundation of Richmond, Inc. |
| March of Dimes Birth Defect Foundation, Greater Blue Ridge Chapter |
| Masonic Home of Virginia |
| Military Family Support Centers, Inc. |
| Moneta Rescue Squad |
| Moneta Volunteer Fire Department |
| Montvale Rescue Squad |
| Mount Pleasant First Aid Crew |
| Mt. Pleasant Volunteer Fire Dept. |
| NAMI Roanoke Valley |
National Multiple Sclerosis Society, Blue Ridge Chapter
New Horizons Health & Wellness Center (formerly Kuumba) |
| NRA Foundation, Inc. |
| On Our Own of Roanoke Valley, Inc. |
| Presbyterian Community Center |
| Presbyterian Home & Family Services |
| Read Mountain Fire & Rescue Department, Company 12 |
| Rebuilding Together, Roanoke, Inc. (formerly Christmas In April) |
| Refugee & Immigration Services |
| Roanoke Adolescent Health Partnership |
| Roanoke Area Ministries |
| Roanoke Emergency Medical Services |
| Roanoke Valley Fund for Deaf Children |
| Roanoke Valley Interfaith Hospitality Network |
| Roanoke Valley Society for the Prevention of Cruelty to Animals (SPCA) |
| Roanoke Valley Therapeutic Riding Program |
| Ronald McDonald House |
| Salem Rescue Squad |
| Scruggs Volunteer Fire Department & Rescue Squad |
| Shady Grove Volunteer Fire & Rescue Squad |
| St. Francis House |
| St. Francis of Assisi Service Dog Foundation |
| St. John's Community Youth Program |
| Stewartsville First Aid & Rescue Crew |
| The Achievement Center |
| Transplants United of Southwest Virginia |
| Unified Human Services Transportation System (RADAR) |
| United Methodist Community Outreach Program of Roanoke |
| Vinton First Aid Crew |
| Virginia Baptist Children's Home and Family Service |
| Virginia Special Olympics |
| Voice of the Blue Ridge |
| West End Center, Inc. |
| Western Virginia Emergency Medical Services Council |
| Youth Support Services, Inc. |
Partner Agency Center
